› 6q0x

Electron Microscopy
4.2Å resolution

The cryo-EM structure of the SNX-BAR Mvp1 tetramer

Released:
DOI: 10.2210/pdb6q0x/pdb
PDB entry 6q0x coloured by chain, front view.
PDB entry 6q0x coloured by chain, side view.
PDB entry 6q0x coloured by chain, top view.
Source organism: Saccharomyces cerevisiae W303
Primary publication:
The cryo-EM structure of the SNX-BAR Mvp1 tetramer.
Sun D, Varlakhanova NV, Tornabene BA, Ramachandran R, Zhang P, Ford MGJ
OpenAccess logo Nat Commun 11 1506 (2020)
PMID: 32198400
Related structures: EMD-20555

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154220 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin MVP1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 531 amino acids
Theoretical weight: 61.9 KDa
Source organism: Saccharomyces cerevisiae W303
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P40959 (Residues: 1-511; Coverage: 100%)
Gene names: MVP1, YM8270.06, YMR004W
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 4.2Å
Relevant EMDB volumes: EMD-20555
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

5 review citations

Sorting Nexins in Protein Homeostasis.
Hanley et al. (2020)
4 more

2 mentions without citation

A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling.
Suzuki et al. (2021)
1 more