6q92

X-ray diffraction
1.5Å resolution

Crystal structure of human Arginase-1 at pH 7.0 in complex with ABH

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
L-arginine + H(2)O = L-ornithine + urea
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138411 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Arginase-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 342 amino acids
Theoretical weight: 36.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05089 (Residues: 1-322; Coverage: 100%)
Gene name: ARG1
Sequence domains: Arginase family

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P3
Unit cell:
a: 90.38Å b: 90.38Å c: 69.254Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.135 0.135 0.147
Expression system: Escherichia coli