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Catalytic domain of the human ubiquitin-conjugating enzyme UBE2S C118M

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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EC 2.3.2.23: E2 ubiquitin-conjugating enzyme

Reaction catalysed:
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine
Systematic name:
S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine:[E2 ubiquitin-conjugating enzyme] ubiquitinyl transferase
Alternative Name(s):
  • UBC
  • Ubiquitin-carrier-protein E2
  • Ubiquitin-conjugating enzyme E2

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00179
Domain description: Ubiquitin-conjugating enzyme
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 S
The deposited structure of PDB entry 6qh3 contains 2 copies of Pfam domain PF00179 (Ubiquitin-conjugating enzyme) in Ubiquitin-conjugating enzyme E2 S. Showing 1 copy in chain B [auth A].

InterPro InterPro annotations
IPR000608
Domain description: Ubiquitin-conjugating enzyme E2
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 S
IPR016135
Domain description: Ubiquitin-conjugating enzyme/RWD-like
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 S
IPR023313
Domain description: Ubiquitin-conjugating enzyme, active site
Occurring in:
  1. Ubiquitin-conjugating enzyme E2 S

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