6qig

X-ray diffraction
2.8Å resolution

Metalloproteinase

Released:
Model geometry
Fit model/data

Function and Biology Details

Reaction catalysed:
The enzyme cleaves the von Willebrand factor at bond 842-Tyr-|-Met-843 within the A2 domain
Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-212455 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (7 distinct):
Antibody Light Chain Chain: L
Molecule details ›
Chain: L
Length: 213 amino acids
Theoretical weight: 23.51 KDa
Source organism: Rattus norvegicus
Antibody Heavy Chain Chain: H
Molecule details ›
Chain: H
Length: 227 amino acids
Theoretical weight: 24.44 KDa
Source organism: Rattus norvegicus
A disintegrin and metalloproteinase with thrombospondin motifs 13 Chain: A

Ligands and Environments

Carbohydrate polymer : NEW Components: MAN, NAG, BMA
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: P3221
Unit cell:
a: 87.532Å b: 87.532Å c: 407.342Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.208 0.206 0.247
Expression system: Drosophila melanogaster