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Cryo-EM structure of calcium-bound nhTMEM16 lipid scramblase in DDM

Source organism: Fusarium vanettenii 77-13-4
Biochemical function: metal ion binding
Biological process: chloride transmembrane transport
Cellular component: cortical endoplasmic reticulum

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF04547
Domain description: Calcium-activated chloride channel
Occurring in:
  1. Plasma membrane channel protein
The deposited structure of PDB entry 6qm5 contains 2 copies of Pfam domain PF04547 (Calcium-activated chloride channel) in Plasma membrane channel protein. Showing 1 copy in chain A.

PF20877
Domain description: Alpha-beta plait domain in TMEM16 lipid scramblase
Occurring in:
  1. Plasma membrane channel protein
The deposited structure of PDB entry 6qm5 contains 2 copies of Pfam domain PF20877 (Alpha-beta plait domain in TMEM16 lipid scramblase) in Plasma membrane channel protein. Showing 1 copy in chain A.

InterPro InterPro annotation
IPR007632
Domain description: Anoctamin
Occurring in:
  1. Plasma membrane channel protein

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