› 6qrn

X-ray diffraction
1.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Galectin-10 Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q05315 (Residues: 1-142; Coverage: 100%)
Gene names: CLC, LGALS10, LGALS10A
Sequence domains: Galactoside-binding lectin

Ligands and Environments

1 bound ligand:
Ligand RIP 1 x RIP
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)
Spacegroup: P6522
Unit cell:
a: 49.139Å b: 49.139Å c: 261.025Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.172 0.171 0.192
Expression system: Escherichia coli BL21

Quick links

Citations

43 review citations

Intersection of biology and therapeutics: type 2 targeted therapeutics for adult asthma.
Peters et al. (2020)
42 more

PDB-REDO

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