Function and Biology

CryoEM structure of the human ClC-1 chloride channel, CBS state 3

Source organism: Homo sapiens
Biochemical function: protein homodimerization activity
Biological process: chloride transmembrane transport
Cellular component: sarcolemma

Sequence family

Pfam Protein family (Pfam)
PF00654
Domain description: Voltage gated chloride channel
Occurring in:
  1. Chloride channel protein 1
The deposited structure of PDB entry 6qvb contains 2 copies of Pfam domain PF00654 (Voltage gated chloride channel) in Chloride channel protein 1. Showing 1 copy in chain B [auth A].

InterPro InterPro annotations
IPR001807
Domain description: Chloride channel, voltage gated
Occurring in:
  1. Chloride channel protein 1
IPR002243
Domain description: Chloride channel ClC-1
Occurring in:
  1. Chloride channel protein 1
IPR046342
Domain description: CBS domain superfamily
Occurring in:
  1. Chloride channel protein 1
IPR014743
Domain description: Chloride channel, core
Occurring in:
  1. Chloride channel protein 1