Function and Biology

Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system

Source organism: Streptococcus thermophilus
Biochemical function: metal ion binding
Biological process: defense response to virus
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF01867
Domain description: CRISPR associated protein Cas1
Occurring in:
  1. CRISPR-associated endonuclease Cas1
The deposited structure of PDB entry 6qxt contains 24 copies of Pfam domain PF01867 (CRISPR associated protein Cas1) in CRISPR-associated endonuclease Cas1. Showing 1 copy in chain I.

PF09711
Domain description: CRISPR-associated protein (Cas_Csn2)
Occurring in:
  1. CRISPR-associated protein Csn2
The deposited structure of PDB entry 6qxt contains 16 copies of Pfam domain PF09711 (CRISPR-associated protein (Cas_Csn2)) in CRISPR-associated protein Csn2. Showing 1 copy in chain BA [auth b].

PF09827
Domain description: CRISPR associated protein Cas2
Occurring in:
  1. CRISPR-associated endoribonuclease Cas2
The deposited structure of PDB entry 6qxt contains 12 copies of Pfam domain PF09827 (CRISPR associated protein Cas2) in CRISPR-associated endoribonuclease Cas2. Showing 1 copy in chain WA [auth w].

InterPro InterPro annotations
IPR002729
Domain description: CRISPR-associated protein Cas1
Occurring in:
  1. CRISPR-associated endonuclease Cas1
IPR010146
Domain description: CRISPR-associated protein, Csn2-type
Occurring in:
  1. CRISPR-associated protein Csn2
IPR038600
Domain description: CRISPR-associated protein Csn2 superfamily
Occurring in:
  1. CRISPR-associated protein Csn2
IPR021127
Domain description: CRISPR-associated endonuclease Cas2
Occurring in:
  1. CRISPR-associated endoribonuclease Cas2
IPR042206
Domain description: CRISPR-associated endonuclease Cas1, C-terminal domain
Occurring in:
  1. CRISPR-associated endonuclease Cas1
IPR019855
Domain description: CRISPR-associated protein Cas1, NMENI subtype
Occurring in:
  1. CRISPR-associated endonuclease Cas1
IPR019199
Domain description: Virulence-associated protein D / CRISPR associated protein Cas2
Occurring in:
  1. CRISPR-associated endoribonuclease Cas2