› 6r45

X-ray diffraction
1.78Å resolution

Crystal structure of eukaryotic O-GlcNAcase HAT-like domain

Released:
DOI: 10.2210/pdb6r45/pdb
PDB entry 6r45 coloured by chain, front view.
PDB entry 6r45 coloured by chain, side view.
PDB entry 6r45 coloured by chain, top view.
Source organism: Trichoplax adhaerens
Entry authors: Raimi OG, Gorelik A, Hopkins-Navratilova I, Aristotelous T, Ferenbach A, vanAalten D

Function and Biology Details

Reaction catalysed: 
[Protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine + H(2)O = [protein]-L-serine + N-acetyl-D-glucosamine
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-101119 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GH84 domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 211 amino acids
Theoretical weight: 24.83 KDa
Source organism: Trichoplax adhaerens
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0D5X2Y8 (Residues: 513-723; Coverage: 29%)

Ligands and Environments

1 bound ligand:
Ligand TRS 1 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE MASSIF-1
Spacegroup: P1
Unit cell:
a: 43.25Å b: 43.52Å c: 59.84Å
α: 87.52° β: 85.24° γ: 87.58°
R-values:
R R work R free
0.194 0.193 0.24
Expression system: Escherichia coli

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