› 6rcl

X-ray diffraction
1.97Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195193 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Oligoribonuclease, mitochondrial Chains: A, B
Molecule details ›
Chains: A, B
Length: 180 amino acids
Theoretical weight: 20.85 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y3B8 (Residues: 39-216; Coverage: 75%)
Gene names: CGI-114, REXO2, SFN, SMFN
Sequence domains: Exonuclease
RNA (5'-R(P*AP*A)-3') Chain: C
Molecule details ›
Chain: C
Length: 2 nucleotides
Theoretical weight: 613 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:
Ligand ZN 1 x ZN
Ligand MG 1 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: C2221
Unit cell:
a: 35.613Å b: 125.835Å c: 167.91Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.205 0.203 0.25
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

6 review citations

Organization and expression of the mammalian mitochondrial genome.
Rackham et al. (2022)
5 more

1 mention without citation

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.
Nicholls et al. (2019)