› 6rd2

X-ray diffraction
1Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167372 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein enabled homolog Chains: A, B
Molecule details ›
Chains: A, B
Length: 113 amino acids
Theoretical weight: 12.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: Q8N8S7 (Residues: 1-111; Coverage: 19%)
Gene names: ENAH, MENA
Sequence domains: WH1 domain
THR-GLU-ASP-GLU-NLW Chains: C, D
Molecule details ›
Chains: C, D
Length: 5 amino acids
Theoretical weight: 605 Da
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand NO3 10 x NO3
Ligand GOL 3 x GOL
Ligand K1N 2 x K1N
1 modified residue:
Ligand NLW 2 x NLW

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: C2
Unit cell:
a: 148.39Å b: 44Å c: 34.83Å
α: 90° β: 102.17° γ: 90°
R-values:
R R work R free
0.199 0.198 0.224
Expression systems:
  • Escherichia coli 'BL21-Gold(DE3)pLysS AG'
  • Not provided

Quick links

Citations

4 review citations

Migration and homeostasis of regulatory T cells in rheumatoid arthritis.
Kotschenreuther et al. (2022)
3 more

1 mention without citation

A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers.
Hwang et al. (2021)