› 6rg2

X-ray diffraction
1.12Å resolution

Photorhabdus laumondii lectin PLL2 in complex with 3-O-methyl-D-glucose

Released:
DOI: 10.2210/pdb6rg2/pdb
PDB entry 6rg2 coloured by chain, front view.
PDB entry 6rg2 coloured by chain, side view.
PDB entry 6rg2 coloured by chain, top view.
Source organism: Photorhabdus laumondii subsp. laumondii TTO1
Primary publication:
Heptabladed β-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.
Fujdiarová E, Houser J, Dobeš P, Paulíková G, Kondakov N, Kononov L, Hyršl P, Wimmerová M
FEBS J 288 1343-1365 (2021)
PMID: 32559333

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181802 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bulb-type lectin domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 371 amino acids
Theoretical weight: 40.15 KDa
Source organism: Photorhabdus laumondii subsp. laumondii TTO1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7N8I8 (Residues: 1-371; Coverage: 100%)
Gene name: plu0734
Sequence domains: Repeat of unknown function (DUF346)

Ligands and Environments

4 bound ligands:
Ligand ZB1 5 x ZB1
Ligand 3MG 14 x 3MG
Ligand ACT 5 x ACT
Ligand NA 2 x NA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P21
Unit cell:
a: 51.646Å b: 56.708Å c: 108.477Å
α: 90° β: 95.33° γ: 90°
R-values:
R R work R free
0.138 0.136 0.161
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Cyclodepsipeptides: Isolation from Endophytic Fungi of Sarcophyton ehrenbergi and Verification of Their Larvicidal Activity via In-Vitro and In-Silico Studies.
Singab et al. (2022)

2 mentions without citation

Heptabladed β-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.
Fujdiarová et al. (2021)
1 more