› 6rgr

X-ray diffraction
1.89Å resolution

Photorhabdus asymbiotica lectin PHL in complex with L-rhamnose

Released:
DOI: 10.2210/pdb6rgr/pdb
PDB entry 6rgr coloured by chain, front view.
PDB entry 6rgr coloured by chain, side view.
PDB entry 6rgr coloured by chain, top view.
Source organism: Photorhabdus asymbiotica
Primary publication:
Heptabladed β-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.
Fujdiarová E, Houser J, Dobeš P, Paulíková G, Kondakov N, Kononov L, Hyršl P, Wimmerová M
FEBS J 288 1343-1365 (2021)
PMID: 32559333

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-111675 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bulb-type lectin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 369 amino acids
Theoretical weight: 40.21 KDa
Source organism: Photorhabdus asymbiotica
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: C7BLE4 (Residues: 1-369; Coverage: 100%)
Gene name: PAU_00698

Ligands and Environments

4 bound ligands:
Ligand EDO 2 x EDO
Ligand RM4 2 x RM4
Ligand NA 4 x NA
Ligand CL 3 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.3
Spacegroup: P3121
Unit cell:
a: 80.499Å b: 80.499Å c: 113.413Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.201 0.2 0.229
Expression system: Escherichia coli BL21(DE3)

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Citations

1 citations in other articles

Cyclodepsipeptides: Isolation from Endophytic Fungi of Sarcophyton ehrenbergi and Verification of Their Larvicidal Activity via In-Vitro and In-Silico Studies.
Singab et al. (2022)

1 mention without citation

Heptabladed β-propeller lectins PLL2 and PHL from Photorhabdus spp. recognize O-methylated sugars and influence the host immune system.
Fujdiarová et al. (2021)