Function and Biology

Cryo-EM structure of the E. coli cytochrome bd-I oxidase at 2.68 A resolution

Source organism: Escherichia coli K-12
Biochemical function: protein binding
Biological process: aerobic electron transport chain
Cellular component: cytochrome complex

EC 7.1.1.7: Ubiquinol oxidase (electrogenic, proton-motive force generating)

Reaction catalysed:
(1a) 2 ubiquinol = 2 ubiquinone + 4 H(+)(Side 1) + 4 e(-)
Systematic name:
Ubiquinol:oxygen oxidoreductase (electrogenic, non H(+)-transporting)
Alternative Name(s):
  • CydA (gene name)
  • CydB (gene name)
  • Cytochrome bd-I oxidase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF08173
Domain description: Membrane bound YbgT-like protein
Occurring in:
  1. Cytochrome bd-I ubiquinol oxidase subunit X
The deposited structure of PDB entry 6rko contains 1 copy of Pfam domain PF08173 (Membrane bound YbgT-like protein) in Cytochrome bd-I ubiquinol oxidase subunit X. Showing 1 copy in chain D [auth X].

PF02322
Domain description: Cytochrome bd terminal oxidase subunit II
Occurring in:
  1. Cytochrome bd-I ubiquinol oxidase subunit 2
The deposited structure of PDB entry 6rko contains 1 copy of Pfam domain PF02322 (Cytochrome bd terminal oxidase subunit II) in Cytochrome bd-I ubiquinol oxidase subunit 2. Showing 1 copy in chain A [auth B].

PF01654
Domain description: Cytochrome bd terminal oxidase subunit I
Occurring in:
  1. Cytochrome bd-I ubiquinol oxidase subunit 1
The deposited structure of PDB entry 6rko contains 1 copy of Pfam domain PF01654 (Cytochrome bd terminal oxidase subunit I) in Cytochrome bd-I ubiquinol oxidase subunit 1. Showing 1 copy in chain B [auth A].

InterPro InterPro annotations
IPR003317
Domain description: Cytochrome ubiquinol oxidase subunit 2
Occurring in:
  1. Cytochrome bd-I ubiquinol oxidase subunit 2
IPR002585
Domain description: Cytochrome ubiquinol oxidase subunit 1
Occurring in:
  1. Cytochrome bd-I ubiquinol oxidase subunit 1
IPR012994
Domain description: Membrane bound YbgT-like
Occurring in:
  1. Cytochrome bd-I ubiquinol oxidase subunit X
IPR011724
Domain description: Cyd operon protein YbgT
Occurring in:
  1. Cytochrome bd-I ubiquinol oxidase subunit X
IPR047743
Domain description: Membrane protein YnhF-like
Occurring in:
  1. Uncharacterized protein YnhF