Function and Biology Details
Reaction catalysed:
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero hexamer (preferred)
Assembly name:
Dipeptidyl peptidase 1 heavy chain (preferred)
PDBe Complex ID:
PDB-CPX-156843 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Dipeptidyl peptidase 1 exclusion domain chain
Molecule details ›
Chains: A, D
Length: 119 amino acids
Theoretical weight: 13.5 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Cathepsin C exclusion domain
Length: 119 amino acids
Theoretical weight: 13.5 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical:
P53634 (Residues: 25-143; Coverage: 27%)
Sequence domains: Cathepsin C exclusion domain
Dipeptidyl peptidase 1 heavy chain
Molecule details ›
Chains: B, E
Length: 163 amino acids
Theoretical weight: 18.37 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Sequence domains: Papain family cysteine protease
Length: 163 amino acids
Theoretical weight: 18.37 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P53634 (Residues: 230-391; Coverage: 37%)
Sequence domains: Papain family cysteine protease
Dipeptidyl peptidase 1 light chain
Molecule details ›
Chains: C, F
Length: 69 amino acids
Theoretical weight: 7.58 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
Length: 69 amino acids
Theoretical weight: 7.58 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
- Canonical: P53634 (Residues: 395-463; Coverage: 16%)
