› 6rth

X-ray diffraction
3.4Å resolution

Crystal structure of the ligand-free glycosyltransferase domain from the YGT toxin

Released:
DOI: 10.2210/pdb6rth/pdb
PDB entry 6rth coloured by chain, front view.
PDB entry 6rth coloured by chain, side view.
PDB entry 6rth coloured by chain, top view.
Source organism: Yersinia mollaretii ATCC 43969
Primary publication:
Inverse control of Rab proteins by Yersinia ADP-ribosyltransferase and glycosyltransferase related to clostridial glucosylating toxins.
Ost GS, Wirth C, Bogdanović X, Kao WC, Schorch B, Aktories PJK, Papatheodorou P, Schwan C, Schlosser A, Jank T, Hunte C, Aktories K
OpenAccess logo Sci Adv 6 eaaz2094 (2020)
PMID: 32195351

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-167417 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
RTX toxin and Ca2+-binding protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 521 amino acids
Theoretical weight: 59.65 KDa
Source organism: Yersinia mollaretii ATCC 43969
Expression system: Escherichia coli

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P212121
Unit cell:
a: 47.178Å b: 161.737Å c: 162.971Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.228 0.227 0.249
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Large Clostridial Toxins: Mechanisms and Roles in Disease.
Orrell et al. (2021)
1 more

2 mentions without citation

Inverse control of Rab proteins by Yersinia ADP-ribosyltransferase and glycosyltransferase related to clostridial glucosylating toxins.
Ost et al. (2020)
1 more