Function and Biology Details
Reaction catalysed:
Cleavage of Arg-|-Ser bond in complement component C3 alpha-chain to yield C3a and C3b, and Arg-|- bond in complement component C5 alpha-chain to yield C5a and C5b.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero tetradecamer (preferred)
PDBe Complex ID:
PDB-CPX-208315 (preferred)
Entry contents:
7 distinct polypeptide molecules
Macromolecules (10 distinct):
Ligands and Environments
Experiments and Validation Details
X-ray source:
PETRA III, EMBL c/o DESY BEAMLINE P13 (MX1)
Spacegroup:
P212121
Expression systems:
- Escherichia coli
- Homo sapiens