Function and Biology

Crystal structure of the human two pore domain potassium ion channel TASK-1 (K2P3.1) in a closed conformation with a bound inhibitor BAY 1000493

Source organism: Homo sapiens
Biochemical function: potassium channel activity
Biological process: potassium ion transmembrane transport
Cellular component: membrane

GO terms

Sequence family

Pfam Protein family (Pfam)
PF07885
Domain description: Ion channel
Occurring in:
  1. Potassium channel subfamily K member 3
The deposited structure of PDB entry 6rv3 contains 8 copies of Pfam domain PF07885 (Ion channel) in Potassium channel subfamily K member 3. Showing 2 copies in chain D.

InterPro InterPro annotations
IPR003092
Domain description: Two pore domain potassium channel, TASK family
Occurring in:
  1. Potassium channel subfamily K member 3
IPR003280
Domain description: Two pore domain potassium channel
Occurring in:
  1. Potassium channel subfamily K member 3
IPR005406
Domain description: Potassium channel subfamily K member 3
Occurring in:
  1. Potassium channel subfamily K member 3
IPR013099
Domain description: Potassium channel domain
Occurring in:
  1. Potassium channel subfamily K member 3