› 6rzu

Electron Microscopy
14.7Å resolution

Structure of s-Mgm1 decorating the outer surface of tubulated lipid membranes in the GTPgammaS bound state

Released:
DOI: 10.2210/pdb6rzu/pdb
PDB entry 6rzu coloured by chain, front view.
PDB entry 6rzu coloured by chain, side view.
PDB entry 6rzu coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1.
Faelber K, Dietrich L, Noel JK, Wollweber F, Pfitzner AK, Mühleip A, Sánchez R, Kudryashev M, Chiaruttini N, Lilie H, Schlegel J, Rosenbaum E, Hessenberger M, Matthaeus C, Kunz S, von der Malsburg A, Noé F, Roux A, van der Laan M, Kühlbrandt W, Daumke O
Nature 571 429-433 (2019)
PMID: 31292547
Related structures: EMD-10063

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124115 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dynamin-like GTPase MGM1, small form Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 695 amino acids
Theoretical weight: 77.36 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli
UniProt:
  • Canonical: G0SGC7 (Residues: 219-913; Coverage: 74%)
Gene names: CTHT_0065850, MGM1
Sequence domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 14.7Å
Relevant EMDB volumes: EMD-10063
Expression system: Escherichia coli

Quick links

Citations

24 review citations

The cell biology of mitochondrial membrane dynamics.
Giacomello et al. (2020)
23 more

1 mention without citation

Cryo-EM structures of S-OPA1 reveal its interactions with membrane and changes upon nucleotide binding.
Zhang et al. (2020)