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Resting state of the E. coli Mre11-Rad50 (SbcCD) head complex bound to ATPgS

Source organism: Escherichia coli
Biochemical function: double-stranded DNA endonuclease activity
Biological process: DNA recombination
Cellular component: DNA repair complex

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF13558
Domain description: SbcC/RAD50-like, Walker B motif
Occurring in:
  1. Nuclease SbcCD subunit C
The deposited structure of PDB entry 6s6v contains 2 copies of Pfam domain PF13558 (SbcC/RAD50-like, Walker B motif) in Nuclease SbcCD subunit C. Showing 1 copy in chain C.

PF13476
Domain description: AAA domain
Occurring in:
  1. Nuclease SbcCD subunit C
The deposited structure of PDB entry 6s6v contains 2 copies of Pfam domain PF13476 (AAA domain) in Nuclease SbcCD subunit C. Showing 1 copy in chain C.

PF12320
Domain description: Type 5 capsule protein repressor C-terminal domain
Occurring in:
  1. Nuclease SbcCD subunit D
The deposited structure of PDB entry 6s6v contains 2 copies of Pfam domain PF12320 (Type 5 capsule protein repressor C-terminal domain) in Nuclease SbcCD subunit D. Showing 1 copy in chain A.

PF00149
Domain description: Calcineurin-like phosphoesterase
Occurring in:
  1. Nuclease SbcCD subunit D
The deposited structure of PDB entry 6s6v contains 2 copies of Pfam domain PF00149 (Calcineurin-like phosphoesterase) in Nuclease SbcCD subunit D. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. Nuclease SbcCD subunit C
IPR029052
Domain description: Metallo-dependent phosphatase-like
Occurring in:
  1. Nuclease SbcCD subunit D
IPR038729
Domain description: Rad50/SbcC-type AAA domain
Occurring in:
  1. Nuclease SbcCD subunit C
IPR004592
Domain description: Nuclease SbcC, gammaproteobacteria type
Occurring in:
  1. Nuclease SbcCD subunit C
IPR026843
Domain description: Nuclease SbcCD subunit D, C-terminal domain
Occurring in:
  1. Nuclease SbcCD subunit D
IPR041796
Domain description: DNA double-strand break repair protein Mre11, N-terminal metallophosphatase domain
Occurring in:
  1. Nuclease SbcCD subunit D
IPR004843
Domain description: Calcineurin-like phosphoesterase domain, ApaH type
Occurring in:
  1. Nuclease SbcCD subunit D
IPR004593
Domain description: Nuclease SbcCD subunit D
Occurring in:
  1. Nuclease SbcCD subunit D

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