Function and Biology Details
Reactions catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
NTP + H(2)O = NDP + phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero 240-mer (preferred)
Assembly name:
VP4/VP2 protein and Capsid protein VP3 (preferred)
PDBe Complex ID:
PDB-CPX-505241 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Capsid protein VP1
Molecule details ›
Chain: A
Length: 298 amino acids
Theoretical weight: 33.29 KDa
Source organism: Human rhinovirus 89 ATCC VR-1199
UniProt:
Length: 298 amino acids
Theoretical weight: 33.29 KDa
Source organism: Human rhinovirus 89 ATCC VR-1199
UniProt:
- Canonical:
P07210 (Residues: 575-872; Coverage: 14%)
Capsid protein VP2
Molecule details ›
Chain: B
Length: 267 amino acids
Theoretical weight: 29.42 KDa
Source organism: Human rhinovirus 89 ATCC VR-1199
UniProt:
Length: 267 amino acids
Theoretical weight: 29.42 KDa
Source organism: Human rhinovirus 89 ATCC VR-1199
UniProt:
- Canonical: P07210 (Residues: 70-336; Coverage: 12%)
Capsid protein VP3
Molecule details ›
Chain: C
Length: 238 amino acids
Theoretical weight: 26.33 KDa
Source organism: Human rhinovirus 89 ATCC VR-1199
UniProt:
Length: 238 amino acids
Theoretical weight: 26.33 KDa
Source organism: Human rhinovirus 89 ATCC VR-1199
UniProt:
- Canonical: P07210 (Residues: 337-574; Coverage: 11%)
VP4/VP2 protein
Molecule details ›
Chain: D
Length: 69 amino acids
Theoretical weight: 7.46 KDa
Source organism: Human rhinovirus 89 ATCC VR-1199
UniProt:
Length: 69 amino acids
Theoretical weight: 7.46 KDa
Source organism: Human rhinovirus 89 ATCC VR-1199
UniProt:
- Canonical: D3KZ50 (Residues: 1-69; Coverage: 49%)
