› 6so9

Solution NMR

Mouse RBM20 RRM domain in complex with AUCUUA RNA

Released:
DOI: 10.2210/pdb6so9/pdb
PDB entry 6so9 coloured by chain, ensemble of 25 models, front view.
PDB entry 6so9 coloured by chain, ensemble of 25 models, side view.
PDB entry 6so9 coloured by chain, ensemble of 25 models, top view.
Source organisms:
Primary publication:
Structural basis of UCUU RNA motif recognition by splicing factor RBM20.
Upadhyay SK, Mackereth CD
OpenAccess logo Nucleic Acids Res 48 4538-4550 (2020)
PMID: 32187365

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174859 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
RNA-binding protein 20 Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.57 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3UQS8 (Residues: 513-621; Coverage: 9%)
Gene name: Rbm20
AUCUUA Chain: B
Molecule details ›
Chain: B
Length: 6 nucleotides
Theoretical weight: 1.76 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 88%
Refinement method: simulated annealing
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

5 review citations

New Insights in RBM20 Cardiomyopathy.
Lennermann et al. (2020)
4 more

2 mentions without citation

ARIAweb: a server for automated NMR structure calculation.
Allain et al. (2020)
1 more