Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134231 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (4 distinct):
Insulin receptor subunit alpha
Molecule details ›
Chains: A, C
Length: 719 amino acids
Theoretical weight: 82.55 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 719 amino acids
Theoretical weight: 82.55 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
P06213 (Residues: 28-746; Coverage: 53%)
Sequence domains:
Insulin receptor subunit beta
Molecule details ›
Chains: B, D
Length: 162 amino acids
Theoretical weight: 18.51 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 162 amino acids
Theoretical weight: 18.51 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: P06213 (Residues: 795-956; Coverage: 12%)
Sequence domains:
Insulin A chain
Insulin B chain
