6svm

X-ray diffraction
2.48Å resolution

Crystal structure of human GFAT-1 in complex with Glucose-6-Phosphate, L-Glu, and UDP-GalNAc

Released:
Model geometry
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Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-170307 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 687 amino acids
Theoretical weight: 77.7 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q06210 (Residues: 1-317, 318-699; Coverage: 97%)
  • Best match: Q06210-2 (Residues: 1-299, 300-681)
Gene names: GFAT, GFPT, GFPT1
Sequence domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P41212
Unit cell:
a: 151.995Å b: 151.995Å c: 165.803Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.189 0.222
Expression system: Spodoptera frugiperda