› 6t3j

X-ray diffraction
3.05Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-279323 (preferred)
Entry contents:
5 distinct polypeptide molecules
Macromolecules (5 distinct):
IgG1-hDR5-01-Heavy Chain Chains: A, F
Molecule details ›
Chains: A, F
Length: 232 amino acids
Theoretical weight: 25.1 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
IgG1-hDR5-01-Light Chain Chains: B, G
Molecule details ›
Chains: B, G
Length: 214 amino acids
Theoretical weight: 23.44 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
IgG1-hDR5-05-Heavy Chain Chains: C, H
IgG1-hDR5-05-Light Chain Chains: D, I
Tumor necrosis factor receptor superfamily member 10B Chains: E, J

Ligands and Environments

No bound ligands
1 modified residue:
Ligand SEP 2 x SEP

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 121.604Å b: 90.926Å c: 138.379Å
α: 90° β: 103.79° γ: 90°
R-values:
R R work R free
0.251 0.25 0.282
Expression system: Homo sapiens

Quick links

Citations

8 review citations

Avidity in antibody effector functions and biotherapeutic drug design.
Oostindie et al. (2022)
7 more