6t4q

Electron Microscopy
2.6Å resolution

Structure of yeast 80S ribosome stalled on the CGA-CCG inhibitory codon combination.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero 82-mer (preferred)
PDBe Complex ID:
PDB-CPX-103559 (preferred)
Entry contents:
75 distinct polypeptide molecules
7 distinct RNA molecules
Macromolecules (82 distinct):
Small ribosomal subunit protein eS1A Chain: SB
Molecule details ›
Chain: SB
Length: 232 amino acids
Theoretical weight: 26.31 KDa
Source organism: Saccharomyces cerevisiae
Small ribosomal subunit protein uS19 Chain: SP
Molecule details ›
Chain: SP
Length: 117 amino acids
Theoretical weight: 13.27 KDa
Source organism: Saccharomyces cerevisiae
Small ribosomal subunit protein uS5 Chain: SC
Small ribosomal subunit protein uS3 Chain: SD
Small ribosomal subunit protein eS4A Chain: SE
Rps5p Chain: SF
Small ribosomal subunit protein eS6A Chain: SG
Small ribosomal subunit protein eS7A Chain: SH
Small ribosomal subunit protein eS8A Chain: SI
Small ribosomal subunit protein uS4A Chain: SJ
Small ribosomal subunit protein eS10A Chain: SK
Small ribosomal subunit protein uS17A Chain: SL
Small ribosomal subunit protein eS12 Chain: SM
Small ribosomal subunit protein uS15 Chain: SN
Small ribosomal subunit protein uS11B Chain: SO
Small ribosomal subunit protein uS9A Chain: SQ
Small ribosomal subunit protein eS17A Chain: SR
Small ribosomal subunit protein uS13A Chain: SS
Small ribosomal subunit protein eS19A Chain: ST
Small ribosomal subunit protein uS10 Chain: SU
Small ribosomal subunit protein eS21A Chain: SV
Small ribosomal subunit protein uS8A Chain: SW
Small ribosomal subunit protein uS12A Chain: SX
Small ribosomal subunit protein eS24A Chain: SY
Small ribosomal subunit protein eS25A Chain: SZ
Small ribosomal subunit protein eS26B Chain: Sa
Small ribosomal subunit protein eS27A Chain: Sb
Small ribosomal subunit protein uS14A Chain: Sd
Small ribosomal subunit protein eS30A Chain: Se
Small ribosomal subunit protein eS31 Chain: Sf
Small ribosomal subunit protein RACK1 Chain: Sg
Small ribosomal subunit protein eS28A Chain: Sc
Large ribosomal subunit protein uL2A Chain: LA
Large ribosomal subunit protein uL3 Chain: LB
Large ribosomal subunit protein uL4A Chain: LC
Large ribosomal subunit protein uL18 Chain: LD
Large ribosomal subunit protein eL6B Chain: LE
Large ribosomal subunit protein uL30A Chain: LF
Large ribosomal subunit protein eL8A Chain: LG
Large ribosomal subunit protein uL6A Chain: LH
Large ribosomal subunit protein uL16 Chain: LI
Large ribosomal subunit protein uL5B Chain: LJ
Large ribosomal subunit protein eL13A Chain: LL
Large ribosomal subunit protein eL14A Chain: LM
Large ribosomal subunit protein eL15A Chain: LN
Large ribosomal subunit protein uL13A Chain: LO
Large ribosomal subunit protein uL22A Chain: LP
Large ribosomal subunit protein eL18A Chain: LQ
Large ribosomal subunit protein eL19A Chain: LR
Large ribosomal subunit protein eL20A Chain: LS
Large ribosomal subunit protein eL21A Chain: LT
Large ribosomal subunit protein eL22A Chain: LU
Large ribosomal subunit protein uL14A Chain: LV
Large ribosomal subunit protein eL24A Chain: LW
Large ribosomal subunit protein uL23 Chain: LX
Large ribosomal subunit protein uL24A Chain: LY
Large ribosomal subunit protein eL27A Chain: LZ
Large ribosomal subunit protein uL15 Chain: La
Large ribosomal subunit protein eL29 Chain: Lb
Large ribosomal subunit protein eL30 Chain: Lc
Large ribosomal subunit protein eL31A Chain: Ld
Large ribosomal subunit protein eL32 Chain: Le
Large ribosomal subunit protein eL33A Chain: Lf
Large ribosomal subunit protein eL34A Chain: Lg
Large ribosomal subunit protein uL29A Chain: Lh
Large ribosomal subunit protein eL36A Chain: Li
Large ribosomal subunit protein eL37A Chain: Lj
Large ribosomal subunit protein eL38 Chain: Lk
Large ribosomal subunit protein eL39 Chain: Ll
Large ribosomal subunit protein eL40A Chain: Lm
60S ribosomal protein L41-A Chain: Ln
Large ribosomal subunit protein eL42A Chain: Lo
Large ribosomal subunit protein eL43A Chain: Lp
nascent chain Chain: 8
Small ribosomal subunit protein uS2A Chain: SA
18S Ribosomal RNA Chain: C2
5S ribosomal RNA Chain: C4
5.8S ribosomal RNA Chain: C3
25S ribosomal RNA Chain: C1
Messenger RNA Chain: 5
ICG tRNA Arg (P/P) Chain: 6
tRNA (E/E) Chain: 7

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this EM entry.
Resolution: 2.6Å
Relevant EMDB volumes: EMD-10377
Expression system: Not provided