6t9d

X-ray diffraction
2.9Å resolution

Crystal structure of a bispecific DutaFab in complex with human VEGF121

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
PDBe Complex ID:
PDB-CPX-210651 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
VP mat DutaFab VH chain Chains: AAA, HHH
Molecule details ›
Chains: AAA, HHH
Length: 220 amino acids
Theoretical weight: 23.5 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
VP mat DutaFab VL chain Chains: BBB, LLL
Molecule details ›
Chains: BBB, LLL
Length: 213 amino acids
Theoretical weight: 23.82 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
N-VEGF Chains: CCC, DDD

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: MAX II BEAMLINE I911-3
Spacegroup: P21
Unit cell:
a: 70.08Å b: 107.875Å c: 87.369Å
α: 90° β: 95.34° γ: 90°
R-values:
R R work R free
0.216 0.212 0.28
Expression systems:
  • Homo sapiens
  • Escherichia coli