Articles - 6tbd mentioned but not cited (4)
- Engineering of Ancestors as a Tool to Elucidate Structure, Mechanism, and Specificity of Extant Terpene Cyclase. Schriever K, Saenz-Mendez P, Rudraraju RS, Hendrikse NM, Hudson EP, Biundo A, Schnell R, Syrén PO. J Am Chem Soc 143 3794-3807 (2021)
- Mechanistic Insights into the Formation of the 6,10-Bicyclic Eunicellane Skeleton by the Bacterial Diterpene Synthase Bnd4. Xu B, Tantillo DJ, Rudolf JD. Angew Chem Int Ed Engl 60 23159-23163 (2021)
- Crystal Structure Based Mutagenesis of Cattleyene Synthase Leads to the Generation of Rearranged Polycyclic Diterpenes. Xing B, Xu H, Li A, Lou T, Xu M, Wang K, Xu Z, Dickschat JS, Yang D, Ma M. Angew Chem Int Ed Engl 61 e202209785 (2022)
- Molecular insights into the catalytic promiscuity of a bacterial diterpene synthase. Li Z, Zhang L, Xu K, Jiang Y, Du J, Zhang X, Meng LH, Wu Q, Du L, Li X, Hu Y, Xie Z, Jiang X, Tang YJ, Wu R, Guo RT, Li S. Nat Commun 14 4001 (2023)
Reviews citing this publication (5)
- Engineering functional thermostable proteins using ancestral sequence reconstruction. Thomson RES, Carrera-Pacheco SE, Gillam EMJ. J Biol Chem 298 102435 (2022)
- Hedycaryol - Central Intermediates in Sesquiterpene Biosynthesis, Part II. Xu H, Dickschat JS. Chemistry 28 e202200405 (2022)
- Protein engineering for natural product biosynthesis and synthetic biology applications. Calzini MA, Malico AA, Mitchler MM, Williams GJ. Protein Eng Des Sel 34 gzab015 (2021)
- Decoding Catalysis by Terpene Synthases. Whitehead JN, Leferink NGH, Johannissen LO, Hay S, Scrutton NS. ACS Catal 13 12774-12802 (2023)
- The Biosynthesis Related Enzyme, Structure Diversity and Bioactivity Abundance of Indole-Diterpenes: A Review. Hou Y, Chen M, Sun Z, Ma G, Chen D, Wu H, Yang J, Li Y, Xu X. Molecules 27 6870 (2022)
Articles citing this publication (6)
- Biotechnological potential and initial characterization of two novel sesquiterpene synthases from Basidiomycota Coniophora puteana for heterologous production of δ-cadinol. Ringel M, Dimos N, Himpich S, Haack M, Huber C, Eisenreich W, Schenk G, Loll B, Brück T. Microb Cell Fact 21 64 (2022)
- Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction. Chiang CH, Wymore T, Rodríguez Benítez A, Hussain A, Smith JL, Brooks CL, Narayan ARH. Proc Natl Acad Sci U S A 120 e2218248120 (2023)
- Active Site Loop Engineering Abolishes Water Capture in Hydroxylating Sesquiterpene Synthases. Srivastava PL, Johns ST, Walters R, Miller DJ, Van der Kamp MW, Allemann RK. ACS Catal 13 14199-14204 (2023)
- Comparative analysis of reconstructed ancestral proteins with their extant counterparts suggests primitive life had an alkaline habitat. Fujikawa T, Sasamoto T, Zhao F, Yamagishi A, Akanuma S. Sci Rep 14 398 (2024)
- Recreating the natural evolutionary trend in key microdomains provides an effective strategy for engineering of a thermomicrobial N-demethylase. Xin Y, Shen C, Tang M, Guo Z, Shi Y, Gu Z, Shao J, Zhang L. J Biol Chem 298 101656 (2022)
- Thermoadaptation in an Ancestral Diterpene Cyclase by Altered Loop Stability. Hueting DA, Vanga SR, Syrén PO. J Phys Chem B 126 3809-3821 (2022)