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Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1

Source organisms:
Biochemical function: DNA-directed 5'-3' RNA polymerase activity
Biological process: DNA-templated transcription
Cellular component: nucleus

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EC 2.7.7.6: DNA-directed RNA polymerase

Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Systematic name:
Nucleoside-triphosphate:RNA nucleotidyltransferase (DNA-directed)
Alternative Name(s):
  • C RNA formation factors
  • C ribonucleic acid formation factors
  • DNA-dependent RNA nucleotidyltransferase
  • DNA-dependent RNA polymerase
  • DNA-dependent ribonucleate nucleotidyltransferase
  • Deoxyribonucleic acid-dependent ribonucleic acid polymerase
  • RNA nucleotidyltransferase
  • RNA nucleotidyltransferase (DNA-directed)
  • RNA polymerase
  • RNA polymerase I
  • RNA polymerase II
  • RNA polymerase III
  • RNA transcriptase
  • Ribonucleate nucleotidyltransferase
  • Ribonucleate polymerase
  • Ribonucleic acid nucleotidyltransferase
  • Ribonucleic acid polymerase
  • Ribonucleic acid transcriptase
  • Ribonucleic polymerase
  • Ribonucleic transcriptase
  • Transcriptase

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Superkiller complex protein 8
The deposited structure of PDB entry 6ted contains 7 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Superkiller complex protein 8. Showing 7 copies in chain U [auth W].

PF00467
Domain description: KOW motif
Occurring in:
  1. Transcription elongation factor SPT5
The deposited structure of PDB entry 6ted contains 2 copies of Pfam domain PF00467 (KOW motif) in Transcription elongation factor SPT5. Showing 2 copies in chain X [auth Z].

PF03439
Domain description: Early transcription elongation factor of RNA pol II, NGN section
Occurring in:
  1. Transcription elongation factor SPT5
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF03439 (Early transcription elongation factor of RNA pol II, NGN section) in Transcription elongation factor SPT5. Showing 1 copy in chain X [auth Z].

PF11942
Domain description: Spt5 transcription elongation factor, acidic N-terminal
Occurring in:
  1. Transcription elongation factor SPT5
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF11942 (Spt5 transcription elongation factor, acidic N-terminal) in Transcription elongation factor SPT5. Showing 1 copy in chain X [auth Z] (this domain is out of the observed residue ranges!).

PF06093
Domain description: Spt4/RpoE2 zinc finger
Occurring in:
  1. Transcription elongation factor SPT4
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF06093 (Spt4/RpoE2 zinc finger) in Transcription elongation factor SPT4. Showing 1 copy in chain W [auth Y].

PF05179
Domain description: RNA pol II accessory factor, Cdc73 family, C-terminal
Occurring in:
  1. Parafibromin
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF05179 (RNA pol II accessory factor, Cdc73 family, C-terminal) in Parafibromin. Showing 1 copy in chain V [auth X] (this domain is out of the observed residue ranges!).

PF16050
Domain description: Paf1 complex subunit CDC73 N-terminal
Occurring in:
  1. Parafibromin
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF16050 (Paf1 complex subunit CDC73 N-terminal) in Parafibromin. Showing 1 copy in chain V [auth X].

PF03985
Domain description: Paf1
Occurring in:
  1. RNA polymerase II-associated factor 1 homolog
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF03985 (Paf1 ) in RNA polymerase II-associated factor 1 homolog. Showing 1 copy in chain T [auth V].

PF04004
Domain description: Leo1-like protein
Occurring in:
  1. RNA polymerase-associated protein LEO1
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF04004 (Leo1-like protein) in RNA polymerase-associated protein LEO1. Showing 1 copy in chain S [auth U].

PF03126
Domain description: Plus-3 domain
Occurring in:
  1. RNA polymerase-associated protein RTF1 homolog
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF03126 (Plus-3 domain) in RNA polymerase-associated protein RTF1 homolog. Showing 1 copy in chain Q [auth R].

PF13181
Domain description: Tetratricopeptide repeat
Occurring in:
  1. RNA polymerase-associated protein CTR9 homolog
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF13181 (Tetratricopeptide repeat) in RNA polymerase-associated protein CTR9 homolog. Showing 1 copy in chain P [auth Q].

PF13374
Domain description: Tetratricopeptide repeat
Occurring in:
  1. RNA polymerase-associated protein CTR9 homolog
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF13374 (Tetratricopeptide repeat) in RNA polymerase-associated protein CTR9 homolog. Showing 1 copy in chain P [auth Q].

PF14633
Domain description: SH2 domain
Occurring in:
  1. Transcription elongation factor SPT6
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF14633 (SH2 domain) in Transcription elongation factor SPT6. Showing 1 copy in chain M.

PF00575
Domain description: S1 RNA binding domain
Occurring in:
  1. Transcription elongation factor SPT6
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF00575 (S1 RNA binding domain) in Transcription elongation factor SPT6. Showing 1 copy in chain M.

PF17674
Domain description: HHH domain
Occurring in:
  1. Transcription elongation factor SPT6
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF17674 (HHH domain) in Transcription elongation factor SPT6. Showing 1 copy in chain M.

PF14635
Domain description: Helix-hairpin-helix motif
Occurring in:
  1. Transcription elongation factor SPT6
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF14635 (Helix-hairpin-helix motif ) in Transcription elongation factor SPT6. Showing 1 copy in chain M.

PF14639
Domain description: Holliday-junction resolvase-like of SPT6
Occurring in:
  1. Transcription elongation factor SPT6
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF14639 (Holliday-junction resolvase-like of SPT6 ) in Transcription elongation factor SPT6. Showing 1 copy in chain M.

PF22706
Domain description: Tex central region-like
Occurring in:
  1. Transcription elongation factor SPT6
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF22706 (Tex central region-like) in Transcription elongation factor SPT6. Showing 1 copy in chain M.

PF14641
Domain description: Helix-turn-helix DNA-binding domain of SPT6
Occurring in:
  1. Transcription elongation factor SPT6
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF14641 (Helix-turn-helix DNA-binding domain of SPT6) in Transcription elongation factor SPT6. Showing 1 copy in chain M.

PF14632
Domain description: Acidic N-terminal SPT6
Occurring in:
  1. Transcription elongation factor SPT6
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF14632 (Acidic N-terminal SPT6) in Transcription elongation factor SPT6. Showing 1 copy in chain M (this domain is out of the observed residue ranges!).

PF03604
Domain description: DNA directed RNA polymerase, 7 kDa subunit
Occurring in:
  1. RNA polymerase II, I and III subunit K
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF03604 (DNA directed RNA polymerase, 7 kDa subunit) in RNA polymerase II, I and III subunit K. Showing 1 copy in chain L.

PF13656
Domain description: RNA polymerase Rpb3/Rpb11 dimerisation domain
Occurring in:
  1. DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF13656 (RNA polymerase Rpb3/Rpb11 dimerisation domain) in DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein. Showing 1 copy in chain K.

PF01194
Domain description: RNA polymerases N / 8 kDa subunit
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF01194 (RNA polymerases N / 8 kDa subunit) in DNA-directed RNA polymerases I, II, and III subunit RPABC5. Showing 1 copy in chain J.

PF01096
Domain description: Transcription factor S-II (TFIIS)
Occurring in:
  1. DNA-directed RNA polymerase II subunit RPB9
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF01096 (Transcription factor S-II (TFIIS)) in DNA-directed RNA polymerase II subunit RPB9. Showing 1 copy in chain I.

PF02150
Domain description: RNA polymerases M/15 Kd subunit
Occurring in:
  1. DNA-directed RNA polymerase II subunit RPB9
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF02150 (RNA polymerases M/15 Kd subunit) in DNA-directed RNA polymerase II subunit RPB9. Showing 1 copy in chain I.

PF03870
Domain description: RNA polymerase Rpb8
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC3
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF03870 (RNA polymerase Rpb8) in DNA-directed RNA polymerases I, II, and III subunit RPABC3. Showing 1 copy in chain H.

PF01192
Domain description: RNA polymerase Rpb6
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF01192 (RNA polymerase Rpb6 ) in DNA-directed RNA polymerases I, II, and III subunit RPABC2. Showing 1 copy in chain F.

PF01191
Domain description: RNA polymerase Rpb5, C-terminal domain
Occurring in:
  1. DNA-directed RNA polymerase II subunit E
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF01191 (RNA polymerase Rpb5, C-terminal domain) in DNA-directed RNA polymerase II subunit E. Showing 1 copy in chain E.

PF03871
Domain description: RNA polymerase Rpb5, N-terminal domain
Occurring in:
  1. DNA-directed RNA polymerase II subunit E
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF03871 (RNA polymerase Rpb5, N-terminal domain) in DNA-directed RNA polymerase II subunit E. Showing 1 copy in chain E.

PF03874
Domain description: RNA polymerase Rpb4
Occurring in:
  1. RNA polymerase Rpb4/RPC9 core domain-containing protein
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF03874 (RNA polymerase Rpb4) in RNA polymerase Rpb4/RPC9 core domain-containing protein. Showing 1 copy in chain D.

PF01000
Domain description: RNA polymerase Rpb3/RpoA insert domain
Occurring in:
  1. DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF01000 (RNA polymerase Rpb3/RpoA insert domain) in DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein. Showing 1 copy in chain C.

PF01193
Domain description: RNA polymerase Rpb3/Rpb11 dimerisation domain
Occurring in:
  1. DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF01193 (RNA polymerase Rpb3/Rpb11 dimerisation domain) in DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein. Showing 1 copy in chain C.

PF04560
Domain description: RNA polymerase Rpb2, domain 7
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF04560 (RNA polymerase Rpb2, domain 7) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain B.

PF00562
Domain description: RNA polymerase Rpb2, domain 6
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF00562 (RNA polymerase Rpb2, domain 6) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain B.

PF04567
Domain description: RNA polymerase Rpb2, domain 5
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF04567 (RNA polymerase Rpb2, domain 5) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain B.

PF04566
Domain description: RNA polymerase Rpb2, domain 4
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF04566 (RNA polymerase Rpb2, domain 4) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain B.

PF04565
Domain description: RNA polymerase Rpb2, domain 3
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF04565 (RNA polymerase Rpb2, domain 3) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain B.

PF04561
Domain description: RNA polymerase Rpb2, domain 2
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF04561 (RNA polymerase Rpb2, domain 2) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain B.

PF04563
Domain description: RNA polymerase beta subunit
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
The deposited structure of PDB entry 6ted contains 1 copy of Pfam domain PF04563 (RNA polymerase beta subunit) in DNA-directed RNA polymerase subunit beta. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR000684
Domain description: RNA polymerase II, heptapeptide repeat, eukaryotic
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR001680
Domain description: WD40 repeat
Occurring in:
  1. Superkiller complex protein 8
IPR019734
Domain description: Tetratricopeptide repeat
Occurring in:
  1. RNA polymerase-associated protein CTR9 homolog
IPR005824
Domain description: KOW
Occurring in:
  1. Transcription elongation factor SPT5
IPR011990
Domain description: Tetratricopeptide-like helical domain superfamily
Occurring in:
  1. RNA polymerase-associated protein CTR9 homolog
IPR012340
Domain description: Nucleic acid-binding, OB-fold
Occurring in:
  1. RNA polymerase II subunit G
  2. DNA-directed RNA polymerases I, II, and III subunit RPABC3
  3. Transcription elongation factor SPT6
IPR001222
Domain description: Zinc finger, TFIIS-type
Occurring in:
  1. DNA-directed RNA polymerase II subunit RPB9
IPR005570
Domain description: DNA-directed RNA polymerases I, II, and III subunit RPABC3
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC3
IPR036603
Domain description: RNA polymerase, RBP11-like subunit
Occurring in:
  1. DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
  2. DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
IPR014722
Domain description: Large ribosomal subunit protein uL2, domain 2
Occurring in:
  1. Transcription elongation factor SPT5
IPR020472
Domain description: G-protein beta WD-40 repeat
Occurring in:
  1. Superkiller complex protein 8
IPR004343
Domain description: Plus-3 domain
Occurring in:
  1. RNA polymerase-associated protein RTF1 homolog
IPR036860
Domain description: SH2 domain superfamily
Occurring in:
  1. Transcription elongation factor SPT6
IPR000268
Domain description: DNA-directed RNA polymerase subunit RPABC5/Rpb10
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
IPR014381
Domain description: DNA-directed RNA polymerase subunit Rpo5/Rpb5
Occurring in:
  1. DNA-directed RNA polymerase II subunit E
IPR022800
Domain description: Spt4/RpoE2 zinc finger
Occurring in:
  1. Transcription elongation factor SPT4
IPR009287
Domain description: Transcription initiation Spt4
Occurring in:
  1. Transcription elongation factor SPT4
IPR007133
Domain description: RNA polymerase II associated factor Paf1
Occurring in:
  1. RNA polymerase II-associated factor 1 homolog
IPR007149
Domain description: Leo1-like protein
Occurring in:
  1. RNA polymerase-associated protein LEO1
IPR036128
Domain description: Plus3-like superfamily
Occurring in:
  1. RNA polymerase-associated protein RTF1 homolog
IPR000980
Domain description: SH2 domain
Occurring in:
  1. Transcription elongation factor SPT6
IPR010994
Domain description: RuvA domain 2-like
Occurring in:
  1. Transcription elongation factor SPT6
IPR017072
Domain description: Transcription elongation factor Spt6
Occurring in:
  1. Transcription elongation factor SPT6
IPR006591
Domain description: RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4
Occurring in:
  1. RNA polymerase II, I and III subunit K
IPR029040
Domain description: RNA polymerase subunit RPABC4/transcription elongation factor Spt4
Occurring in:
  1. RNA polymerase II, I and III subunit K
  2. Transcription elongation factor SPT4
IPR001529
Domain description: DNA-directed RNA polymerase, M/15kDa subunit
Occurring in:
  1. DNA-directed RNA polymerase II subunit RPB9
IPR012164
Domain description: DNA-directed RNA polymerase subunit/transcription factor S
Occurring in:
  1. DNA-directed RNA polymerase II subunit RPB9
IPR003029
Domain description: S1 domain
Occurring in:
  1. RNA polymerase II subunit G
  2. Transcription elongation factor SPT6
IPR036898
Domain description: RNA polymerase Rpb7-like, N-terminal domain superfamily
Occurring in:
  1. RNA polymerase II subunit G
IPR006110
Domain description: RNA polymerase, subunit omega/Rpo6/RPB6
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR036161
Domain description: RPB6/omega subunit-like superfamily
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR035913
Domain description: RPB5-like RNA polymerase subunit superfamily
Occurring in:
  1. DNA-directed RNA polymerase II subunit E
IPR036710
Domain description: RNA polymerase Rpb5, N-terminal domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase II subunit E
IPR036643
Domain description: DNA-directed RNA polymerase, insert domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
IPR011263
Domain description: DNA-directed RNA polymerase, RpoA/D/Rpb3-type
Occurring in:
  1. DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
IPR015712
Domain description: DNA-directed RNA polymerase, subunit 2
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR044893
Domain description: RNA polymerase Rpb1, clamp domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR041980
Domain description: Spt5, KOW domain repeat 6
Occurring in:
  1. Transcription elongation factor SPT5
IPR024945
Domain description: Spt5 C-terminal domain
Occurring in:
  1. Transcription elongation factor SPT5
IPR041978
Domain description: Spt5, KOW domain repeat 5
Occurring in:
  1. Transcription elongation factor SPT5
IPR041977
Domain description: Spt5, KOW domain repeat 4
Occurring in:
  1. Transcription elongation factor SPT5
IPR041976
Domain description: Spt5, KOW domain repeat 3
Occurring in:
  1. Transcription elongation factor SPT5
IPR008991
Domain description: Translation protein SH3-like domain superfamily
Occurring in:
  1. Transcription elongation factor SPT5
IPR041975
Domain description: Spt5, KOW domain repeat 2
Occurring in:
  1. Transcription elongation factor SPT5
IPR041973
Domain description: Spt5, KOW domain repeat 1
Occurring in:
  1. Transcription elongation factor SPT5
IPR039385
Domain description: NGN domain, eukaryotic
Occurring in:
  1. Transcription elongation factor SPT5
IPR005100
Domain description: NGN domain
Occurring in:
  1. Transcription elongation factor SPT5
IPR006645
Domain description: NusG-like, N-terminal
Occurring in:
  1. Transcription elongation factor SPT5
IPR036735
Domain description: NusG, N-terminal domain superfamily
Occurring in:
  1. Transcription elongation factor SPT5
IPR022581
Domain description: Spt5 transcription elongation factor, N-terminal
Occurring in:
  1. Transcription elongation factor SPT5
IPR039659
Domain description: Transcription elongation factor SPT5
Occurring in:
  1. Transcription elongation factor SPT5
IPR017071
Domain description: Transcription elongation factor Spt5, eukaryote
Occurring in:
  1. Transcription elongation factor SPT5
IPR038510
Domain description: Spt4 superfamily
Occurring in:
  1. Transcription elongation factor SPT4
IPR031336
Domain description: Cell division control protein 73, C-terminal
Occurring in:
  1. Parafibromin
IPR038103
Domain description: Cell division control protein 73, C-terminal domain superfamily
Occurring in:
  1. Parafibromin
IPR032041
Domain description: Paf1 complex subunit Cdc73, N-terminal domain
Occurring in:
  1. Parafibromin
IPR007852
Domain description: Cdc73/Parafibromin
Occurring in:
  1. Parafibromin
IPR019775
Domain description: WD40 repeat, conserved site
Occurring in:
  1. Superkiller complex protein 8
IPR036322
Domain description: WD40-repeat-containing domain superfamily
Occurring in:
  1. Superkiller complex protein 8
IPR015943
Domain description: WD40/YVTN repeat-like-containing domain superfamily
Occurring in:
  1. Superkiller complex protein 8
IPR031101
Domain description: RNA polymerase-associated protein Ctr9
Occurring in:
  1. RNA polymerase-associated protein CTR9 homolog
IPR035018
Domain description: Spt6, SH2 domain, C terminus
Occurring in:
  1. Transcription elongation factor SPT6
IPR035019
Domain description: Spt6, SH2 domain, N terminus
Occurring in:
  1. Transcription elongation factor SPT6
IPR035420
Domain description: Spt6, SH2 domain
Occurring in:
  1. Transcription elongation factor SPT6
IPR041692
Domain description: HHH domain 9
Occurring in:
  1. Transcription elongation factor SPT6
IPR042066
Domain description: Spt6, Death-like domain
Occurring in:
  1. Transcription elongation factor SPT6
IPR032706
Domain description: Transcription elongation factor Spt6, helix-hairpin-helix motif
Occurring in:
  1. Transcription elongation factor SPT6
IPR037027
Domain description: YqgF/RNase H-like domain superfamily
Occurring in:
  1. Transcription elongation factor SPT6
IPR006641
Domain description: YqgF/RNase H-like domain
Occurring in:
  1. Transcription elongation factor SPT6
IPR012337
Domain description: Ribonuclease H-like superfamily
Occurring in:
  1. Transcription elongation factor SPT6
IPR028231
Domain description: Transcription elongation factor Spt6, YqgF domain
Occurring in:
  1. Transcription elongation factor SPT6
IPR023323
Domain description: Tex-like domain superfamily
Occurring in:
  1. Transcription elongation factor SPT6
IPR028088
Domain description: Helix-turn-helix DNA-binding domain of Spt6
Occurring in:
  1. Transcription elongation factor SPT6
IPR023319
Domain description: Tex-like protein, HTH domain superfamily
Occurring in:
  1. Transcription elongation factor SPT6
IPR028083
Domain description: Spt6 acidic, N-terminal domain
Occurring in:
  1. Transcription elongation factor SPT6
IPR039747
Domain description: DNA-directed RNA polymerases I, II, and III subunit RPABC4
Occurring in:
  1. RNA polymerase II, I and III subunit K
IPR008193
Domain description: DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
IPR009025
Domain description: DNA-directed RNA polymerase, RBP11-like dimerisation domain
Occurring in:
  1. DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
IPR022905
Domain description: DNA-directed RNA polymerase subunit Rpo11-like
Occurring in:
  1. DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
IPR037685
Domain description: RNA polymerase RBP11
Occurring in:
  1. DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein
IPR020789
Domain description: RNA polymerases, subunit N, zinc binding site
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
IPR023580
Domain description: RNA polymerase subunit RPB10
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC5
IPR034012
Domain description: Pol II subunit B9, C-terminal zinc ribbon
Occurring in:
  1. DNA-directed RNA polymerase II subunit RPB9
IPR019761
Domain description: DNA-directed RNA polymerase M, 15kDa subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerase II subunit RPB9
IPR005576
Domain description: RNA polymerase Rpb7-like , N-terminal
Occurring in:
  1. RNA polymerase II subunit G
IPR045113
Domain description: RNA polymerase subunit Rpb7-like
Occurring in:
  1. RNA polymerase II subunit G
IPR020708
Domain description: DNA-directed RNA polymerase, 14-18kDa subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR028363
Domain description: DNA-directed RNA polymerase, subunit RPB6
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR006111
Domain description: Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit
Occurring in:
  1. DNA-directed RNA polymerases I, II, and III subunit RPABC2
IPR020608
Domain description: RNA polymerase, subunit H/Rpb5, conserved site
Occurring in:
  1. DNA-directed RNA polymerase II subunit E
IPR000783
Domain description: RNA polymerase, subunit H/Rpb5 C-terminal
Occurring in:
  1. DNA-directed RNA polymerase II subunit E
IPR005571
Domain description: RNA polymerase, Rpb5, N-terminal
Occurring in:
  1. DNA-directed RNA polymerase II subunit E
IPR005574
Domain description: RNA polymerase subunit Rpb4/RPC9
Occurring in:
  1. RNA polymerase Rpb4/RPC9 core domain-containing protein
IPR006590
Domain description: RNA polymerase Rpb4/RPC9, core
Occurring in:
  1. RNA polymerase Rpb4/RPC9 core domain-containing protein
IPR038324
Domain description: Rpb4/RPC9 superfamily
Occurring in:
  1. RNA polymerase Rpb4/RPC9 core domain-containing protein
IPR045222
Domain description: DNA-directed RNA polymerase II subunit Rpb4-like
Occurring in:
  1. RNA polymerase Rpb4/RPC9 core domain-containing protein
IPR010997
Domain description: HRDC-like superfamily
Occurring in:
  1. RNA polymerase Rpb4/RPC9 core domain-containing protein
IPR011262
Domain description: DNA-directed RNA polymerase, insert domain
Occurring in:
  1. DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
IPR001514
Domain description: DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
IPR022842
Domain description: DNA-directed RNA polymerase subunit Rpo3/Rpb3/RPAC1
Occurring in:
  1. DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein
IPR007641
Domain description: RNA polymerase Rpb2, domain 7
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR007121
Domain description: RNA polymerase, beta subunit, conserved site
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR014724
Domain description: RNA polymerase Rpb2, OB-fold
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR037033
Domain description: DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR007120
Domain description: DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR007647
Domain description: RNA polymerase Rpb2, domain 5
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR007646
Domain description: RNA polymerase Rpb2, domain 4
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR007645
Domain description: RNA polymerase Rpb2, domain 3
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR037034
Domain description: RNA polymerase Rpb2, domain 2 superfamily
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR007642
Domain description: RNA polymerase Rpb2, domain 2
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR007644
Domain description: RNA polymerase, beta subunit, protrusion
Occurring in:
  1. DNA-directed RNA polymerase subunit beta
IPR038593
Domain description: RNA polymerase Rpb1, domain 7 superfamily
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR007073
Domain description: RNA polymerase Rpb1, domain 7
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR007075
Domain description: RNA polymerase Rpb1, domain 6
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR007081
Domain description: RNA polymerase Rpb1, domain 5
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR007083
Domain description: RNA polymerase Rpb1, domain 4
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR038120
Domain description: RNA polymerase Rpb1, funnel domain superfamily
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR042102
Domain description: RNA polymerase Rpb1, domain 3 superfamily
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR007066
Domain description: RNA polymerase Rpb1, domain 3
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR000722
Domain description: RNA polymerase, alpha subunit
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR006592
Domain description: RNA polymerase, N-terminal
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR045867
Domain description: DNA-directed RNA polymerase, subunit beta-prime
Occurring in:
  1. DNA-directed RNA polymerase subunit
IPR007080
Domain description: RNA polymerase Rpb1, domain 1
Occurring in:
  1. DNA-directed RNA polymerase subunit

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