› 6thb

X-ray diffraction
2.78Å resolution

Receptor binding domain of the Cedar Virus attachment glycoprotein (G)

Released:
DOI: 10.2210/pdb6thb/pdb
PDB entry 6thb coloured by chain, front view.
PDB entry 6thb coloured by chain, side view.
PDB entry 6thb coloured by chain, top view.
Source organism: Cedar virus
Primary publication:
A key region of molecular specificity orchestrates unique ephrin-B1 utilization by Cedar virus.
Pryce R, Azarm K, Rissanen I, Harlos K, Bowden TA, Lee B
OpenAccess logo Life Sci Alliance 3 (2020)
PMID: 31862858

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-125331 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Attachment glycoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 426 amino acids
Theoretical weight: 48.82 KDa
Source organism: Cedar virus
Expression system: Homo sapiens
UniProt:
  • Canonical: J7H333 (Residues: 209-622; Coverage: 67%)
Gene name: G
Sequence domains: Haemagglutinin-neuraminidase

Ligands and Environments

1 bound ligand:
Ligand NAG 13 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I02
Spacegroup: P65
Unit cell:
a: 201.46Å b: 201.46Å c: 112.89Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.202 0.201 0.227
Expression system: Homo sapiens

Quick links

Citations

7 review citations

Receptor-mediated cell entry of paramyxoviruses: Mechanisms, and consequences for tropism and pathogenesis.
Navaratnarajah et al. (2020)
6 more

2 mentions without citation

Unraveling virus relationships by structure-based phylogenetic classification.
Ng et al. (2020)
1 more