› 6tob

Solution NMR

Structural and DNA Binding Properties of Mycobacterial Integration Host Factor mIHF

Released:
DOI: 10.2210/pdb6tob/pdb
PDB entry 6tob coloured by chain, ensemble of 20 models, front view.
PDB entry 6tob coloured by chain, ensemble of 20 models, side view.
PDB entry 6tob coloured by chain, ensemble of 20 models, top view.
Source organism: Mycobacterium tuberculosis
Primary publication:
Structural and DNA binding properties of mycobacterial integration host factor mIHF.
Odermatt NT, Lelli M, Herrmann T, Abriata LA, Japaridze A, Voilquin H, Singh R, Piton J, Emsley L, Dietler G, Cole ST
J Struct Biol 209 107434 (2020)
PMID: 31846718

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159811 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integration host factor Chain: A
Molecule details ›
Chain: A
Length: 109 amino acids
Theoretical weight: 11.91 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P71658 (Residues: 1-105; Coverage: 100%)
Gene names: Rv1388, mihF
Sequence domains: S13-like H2TH domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 74%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

1 citations in other articles

Mycobacterial IHF is a highly dynamic nucleoid-associated protein that assists HupB in organizing chromatin.
Hołówka et al. (2023)

1 mention without citation

PeSTo: parameter-free geometric deep learning for accurate prediction of protein binding interfaces.
Krapp et al. (2023)