6twi

X-ray diffraction
2.27Å resolution

Crystal structure of the haemagglutinin mutant (Gln226Leu, Gly228Ser) from an H10N7 seal influenza virus isolated in Germany in complex with avian receptor analogue 3'-SLN

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-100836 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (4 distinct):
Hemagglutinin Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 325 amino acids
Theoretical weight: 35.51 KDa
Source organism: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: A0A0A7HR51 (Residues: 10-332; Coverage: 59%)
Gene name: HA
Sequence domains: Haemagglutinin
Hemagglutinin Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 177 amino acids
Theoretical weight: 20.31 KDa
Source organism: Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: A0A0A7HR51 (Residues: 333-508; Coverage: 32%)
Gene name: HA
Sequence domains: Haemagglutinin

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, GAL, SIA
Carbohydrate polymer : NEW Components: NAG
3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 64.843Å b: 215.101Å c: 78.246Å
α: 90° β: 96.78° γ: 90°
R-values:
R R work R free
0.247 0.245 0.273
Expression system: Spodoptera frugiperda