6tyd

X-ray diffraction
2.8Å resolution

Structure of human LDB1 in complex with SSBP2

Released:
Source organism: Homo sapiens
Primary publication:
Crystal structure of human LDB1 in complex with SSBP2.
Proc Natl Acad Sci U S A 117 1042-1048 (2020)
PMID: 31892537

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-160556 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
LIM domain-binding protein 1 Chain: V
Molecule details ›
Chain: V
Length: 231 amino acids
Theoretical weight: 27.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q86U70 (Residues: 56-285; Coverage: 56%)
Gene names: CLIM2, LDB1
Sequence domains: LIM-domain binding protein
Single-stranded DNA-binding protein 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 95 amino acids
Theoretical weight: 10.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P81877 (Residues: 1-94; Coverage: 26%)
Gene names: SSBP2, SSDP2

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: P6522
Unit cell:
a: 104.322Å b: 104.322Å c: 250.419Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.244 0.24 0.281
Expression system: Escherichia coli