› 6tz9

Electron Microscopy
6.2Å resolution

CryoEM reconstruction of membrane-bound ESCRT-III filament composed of CHMP1B only

Released:
DOI: 10.2210/pdb6tz9/pdb
PDB entry 6tz9 coloured by chain, front view.
PDB entry 6tz9 coloured by chain, side view.
PDB entry 6tz9 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nguyen HC, Talledge N, McCullough J, Sharma A, Moss FR, Iwasa JH, Vershinin MD, Sundquist WI, Frost A
OpenAccess logo Nat Struct Mol Biol 27 392-399 (2020)
PMID: 32251413
Related structures: EMD-20590

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo 26-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181645 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Charged multivesicular body protein 1b Chains: A, AA, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V, W, X, Y, Z
Molecule details ›
Chains: A, AA, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, V, W, X, Y, Z
Length: 199 amino acids
Theoretical weight: 22.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7LBR1 (Residues: 1-199; Coverage: 100%)
Gene names: C18orf2, CHMP1B
Sequence domains: Snf7

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 6.2Å
Relevant EMDB volumes: EMD-20590
Expression system: Escherichia coli

Quick links

Citations

6 review citations

The ESCRTs - converging on mechanism.
Remec Pavlin et al. (2020)
5 more

2 mentions without citation

Membrane constriction and thinning by sequential ESCRT-III polymerization.
Nguyen et al. (2020)
1 more