› 6tzr

X-ray diffraction
2.4Å resolution

A DNA G-quadruplex/i-motif hybrid

Released:
DOI: 10.2210/pdb6tzr/pdb
PDB entry 6tzr coloured by chain, front view.
PDB entry 6tzr coloured by chain, side view.
PDB entry 6tzr coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
A DNA G-quadruplex/i-motif hybrid.
Chu B, Zhang D, Paukstelis PJ
OpenAccess logo Nucleic Acids Res 47 11921-11930 (2019)
PMID: 31724696

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-120664 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*CP*CP*AP*GP*GP*CP*(BRU)P*GP*CP*AP*A)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 11 nucleotides
Theoretical weight: 3.41 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand BA 1 x BA
1 modified residue:
Ligand BRU 2 x BRU

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P3221
Unit cell:
a: 37.099Å b: 37.099Å c: 98.309Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.212 0.254
Expression system: Not provided

Quick links

Citations

4 review citations

Prospects and challenges of dynamic DNA nanostructures in biomedical applications.
Tian et al. (2022)
3 more

1 mention without citation

A DNA G-quadruplex/i-motif hybrid.
Chu et al. (2019)