6u2l

Electron Microscopy
2.83Å resolution

EM structure of MPEG-1 (L425K, beta conformation) soluble pre-pore complex

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo 32-mer (preferred)
PDBe Complex ID:
PDB-CPX-173720 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Macrophage-expressed gene 1 protein Chains: A, AA, B, BB, C, CC, D, DD, E, EE, F, FF, G, GG, H, HH, I, II, J, JJ, K, KK, L, LL, M, MM, N, NN, O, OO, P, PP
Molecule details ›
Chains: A, AA, B, BB, C, CC, D, DD, E, EE, F, FF, G, GG, H, HH, I, II, J, JJ, K, KK, L, LL, M, MM, N, NN, O, OO, P, PP
Length: 642 amino acids
Theoretical weight: 71.13 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q2M385 (Residues: 18-653; Coverage: 91%)
Gene name: MPEG1
Sequence domains: MAC/Perforin domain

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.83Å
Relevant EMDB volumes: EMD-20623
Expression system: Spodoptera frugiperda