› 6u46

Solution NMR

Solution Structure of a Heat-Resistant Long-Acting Insulin Analog

Released:
DOI: 10.2210/pdb6u46/pdb
PDB entry 6u46 coloured by chain, ensemble of 20 models, front view.
PDB entry 6u46 coloured by chain, ensemble of 20 models, side view.
PDB entry 6u46 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Yang Y, Weiss MA

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134181 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Insulin B chain Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.79 KDa
Source organism: Homo sapiens
Expression system: Komagataella phaffii GS115
UniProt:
  • Canonical: P01308 (Residues: 25-109; Coverage: 67%)
Gene name: INS
Sequence domains: Insulin/IGF/Relaxin family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Chemical shift assignment: 58%
Refinement method: simulated annealing
Expression system: Komagataella phaffii GS115

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