› 6uet

Electron Microscopy
4.1Å resolution

SAM-bound SAM-IV riboswitch

Released:
DOI: 10.2210/pdb6uet/pdb
PDB entry 6uet coloured by chain, front view.
PDB entry 6uet coloured by chain, side view.
PDB entry 6uet coloured by chain, top view.
Source organism: Mycobacterium sp. MCS
Primary publication:
Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 Å resolution.
Zhang K, Li S, Kappel K, Pintilie G, Su Z, Mou TC, Schmid MF, Das R, Chiu W
Nat Commun 10 5511 (2019)
PMID: 31796736
Related structures: EMD-20756

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195894 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (119-MER) Chain: A
Molecule details ›
Chain: A
Length: 119 nucleotides
Theoretical weight: 38.52 KDa
Source organism: Mycobacterium sp. MCS
Expression system: Not provided
Sequence domains: S-adenosyl methionine (SAM) riboswitch,

Ligands and Environments

1 bound ligand:
Ligand SAM 1 x SAM
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.1Å
Relevant EMDB volumes: EMD-20756
Expression system: Not provided

Quick links

Citations

21 review citations

Targeting RNA structures with small molecules.
Childs-Disney et al. (2022)
20 more

3 mentions without citation

Recent Insights into the Structure and Function of Mycobacterial Membrane Proteins Facilitated by Cryo-EM.
Bendre et al. (2021)
2 more