› 6ulb

X-ray diffraction
1.75Å resolution

Sex Hormone-binding globulin mutant E176K in complex with Danazol

Released:
DOI: 10.2210/pdb6ulb/pdb
PDB entry 6ulb coloured by chain, front view.
PDB entry 6ulb coloured by chain, side view.
PDB entry 6ulb coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Round PW, Das S, Van Petegem F

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137579 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sex hormone-binding globulin Chain: A
Molecule details ›
Chain: A
Length: 205 amino acids
Theoretical weight: 22.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04278 (Residues: 30-234; Coverage: 55%)
Gene name: SHBG
Sequence domains: Laminin G domain

Ligands and Environments

2 bound ligands:
Ligand CA 1 x CA
Ligand QA1 1 x QA1
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-D
Spacegroup: P4322
Unit cell:
a: 52.007Å b: 52.007Å c: 149.238Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.184 0.225
Expression system: Escherichia coli BL21(DE3)

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