6uye

Electron Microscopy
3.96Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dodecamer (preferred)
PDBe Complex ID:
PDB-CPX-207219 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (7 distinct):
Filoviruses glycoprotein extracellular domain-containing protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 261 amino acids
Theoretical weight: 29.06 KDa
Source organism: Ebola virus
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A068J419 (Residues: 32-292; Coverage: 39%)
Gene name: GP
Sequence domains: Filovirus glycoprotein
Filoviruses glycoprotein extracellular domain-containing protein Chains: D, E, F
Molecule details ›
Chains: D, E, F
Length: 96 amino acids
Theoretical weight: 10.8 KDa
Source organism: Ebola virus
Expression system: Homo sapiens
UniProt:
  • Canonical: A0A068J419 (Residues: 503-598; Coverage: 14%)
Gene name: GP
Sequence domains: Envelope glycoprotein GP2-like, HR1-HR2
Antibody rEBOV-548 Fab, heavy chain Chains: G, H, I
Molecule details ›
Chains: G, H, I
Length: 132 amino acids
Theoretical weight: 14.68 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Antibody rEBOV-548 Fab, light chain Chains: J, K, L
Molecule details ›
Chains: J, K, L
Length: 108 amino acids
Theoretical weight: 11.74 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer : NEW Components: NAG, BMA, MAN
1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.96Å
Relevant EMDB volumes: EMD-20947
Expression system: Homo sapiens