6v17

X-ray diffraction
2.05Å resolution

Crystal structure of the bromodomain of human BRD7 bound to I-BRD9

Released:
Source organism: Homo sapiens

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
PDBe Complex ID:
PDB-CPX-192484 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bromodomain-containing protein 7 Chains: A, B
Molecule details ›
Chains: A, B
Length: 123 amino acids
Theoretical weight: 14.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9NPI1 (Residues: 130-250; Coverage: 19%)
Gene names: BP75, BRD7, CELTIX1
Sequence domains: Bromodomain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: Cu FINE FOCUS
Spacegroup: P212121
Unit cell:
a: 41.102Å b: 64.749Å c: 96.107Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.209 0.241
Expression system: Escherichia coli BL21(DE3)