› 6v1x

Electron Microscopy
3.5Å resolution

Cryo-EM Structure of the Hyperpolarization-Activated Potassium Channel KAT1: Tetramer

Released:
DOI: 10.2210/pdb6v1x/pdb
PDB entry 6v1x coloured by chain, front view.
PDB entry 6v1x coloured by chain, side view.
PDB entry 6v1x coloured by chain, top view.
Source organism: Arabidopsis thaliana
Primary publication:
Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1.
Clark MD, Contreras GF, Shen R, Perozo E
OpenAccess logo Nature 583 145-149 (2020)
PMID: 32461693
Related structures: EMD-21018

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174433 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel KAT1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 512 amino acids
Theoretical weight: 59.64 KDa
Source organism: Arabidopsis thaliana
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q39128 (Residues: 1-502; Coverage: 74%)
Gene names: At5g46240, KAT1, MPL12.2
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand QNP 4 x QNP
Ligand QNJ 4 x QNJ
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-21018
Expression system: Spodoptera frugiperda

Quick links

Citations

6 review citations

Ion channels as lipid sensors: from structures to mechanisms.
Thompson et al. (2020)
5 more

1 mention without citation

Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1.
Clark et al. (2020)