› 6v73

X-ray diffraction
2.4Å resolution

Crystal Structure of Metallo Beta Lactamase from Erythrobacter litoralis with beta mercaptoethanol in the active site

Released:
DOI: 10.2210/pdb6v73/pdb
PDB entry 6v73 coloured by chain, front view.
PDB entry 6v73 coloured by chain, side view.
PDB entry 6v73 coloured by chain, top view.
Source organism: Erythrobacter litoralis HTCC2594
Entry authors: Maltseva N, Kim Y, Clancy S, Endres M, Mulligan R, Joachimiak A, Center for Structural Genomics of Infectious Diseases (CSGID)

Function and Biology Details

Reaction catalysed: 
A beta-lactam + H(2)O = a substituted beta-amino acid
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-558251 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metallo-beta-lactamase type 2 Chain: A
Molecule details ›
Chain: A
Length: 245 amino acids
Theoretical weight: 25.96 KDa
Source organism: Erythrobacter litoralis HTCC2594
Expression system: Not provided
UniProt:
  • Canonical: Q2N9N3 (Residues: 20-261; Coverage: 93%)
Gene name: ELI_07580
Sequence domains: Metallo-beta-lactamase superfamily

Ligands and Environments

4 bound ligands:
Ligand ZN 2 x ZN
Ligand CL 1 x CL
Ligand BME 1 x BME
Ligand FMT 1 x FMT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P6322
Unit cell:
a: 121.139Å b: 121.139Å c: 90.551Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.183 0.18 0.241
Expression system: Not provided

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