Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170249 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ERAD-associated E3 ubiquitin-protein ligase HRD1
Molecule details ›
Chain: B
Length: 430 amino acids
Theoretical weight: 50.27 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Ring finger domain
Length: 430 amino acids
Theoretical weight: 50.27 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
Q08109 (Residues: 1-430; Coverage: 78%)
Sequence domains: Ring finger domain
ERAD-associated E3 ubiquitin-protein ligase component HRD3
Molecule details ›
Chain: A
Length: 767 amino acids
Theoretical weight: 88.24 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains: Sel1 repeat
Length: 767 amino acids
Theoretical weight: 88.24 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: Q05787 (Residues: 1-767; Coverage: 92%)
Sequence domains: Sel1 repeat
