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Human ESCRT-I heterotetramer headpiece

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: endosome transport via multivesicular body sorting pathway
Cellular component: ESCRT I complex

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF03997
Domain description: VPS28 protein
Occurring in:
  1. Vacuolar protein sorting-associated protein 28 homolog
The deposited structure of PDB entry 6vme contains 6 copies of Pfam domain PF03997 (VPS28 protein) in Vacuolar protein sorting-associated protein 28 homolog. Showing 1 copy in chain V [auth W].

PF07200
Domain description: Modifier of rudimentary (Mod(r)) protein
Occurring in:
  1. Vacuolar protein sorting-associated protein 37B
The deposited structure of PDB entry 6vme contains 6 copies of Pfam domain PF07200 (Modifier of rudimentary (Mod(r)) protein) in Vacuolar protein sorting-associated protein 37B. Showing 1 copy in chain B [auth C].

PF09454
Domain description: Vps23 core domain
Occurring in:
  1. Tumor susceptibility gene 101 protein
The deposited structure of PDB entry 6vme contains 6 copies of Pfam domain PF09454 (Vps23 core domain) in Tumor susceptibility gene 101 protein. Showing 1 copy in chain E [auth F].

InterPro InterPro annotations
IPR037202
Domain description: ESCRT assembly domain
Occurring in:
  1. Tumor susceptibility gene 101 protein
  2. Vacuolar protein sorting-associated protein 37B
  3. Vacuolar protein sorting-associated protein 28 homolog
IPR007143
Domain description: Vacuolar protein sorting-associated Vps28
Occurring in:
  1. Vacuolar protein sorting-associated protein 28 homolog
IPR009851
Domain description: Modifier of rudimentary, Modr
Occurring in:
  1. Vacuolar protein sorting-associated protein 37B
IPR017916
Domain description: Steadiness box (SB) domain
Occurring in:
  1. Tumor susceptibility gene 101 protein
IPR038358
Domain description: VPS28, N-terminal domain superfamily
Occurring in:
  1. Vacuolar protein sorting-associated protein 28 homolog
IPR017898
Domain description: Vacuolar protein sorting-associated, VPS28, N-terminal
Occurring in:
  1. Vacuolar protein sorting-associated protein 28 homolog
IPR029012
Domain description: Helix hairpin bin domain superfamily
Occurring in:
  1. Vacuolar protein sorting-associated protein 37B
IPR018798
Domain description: Multivesicular body subunit 12
Occurring in:
  1. Multivesicular body subunit 12A

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