› 6vps

Electron Microscopy
2.6Å resolution

Cryo-EM structure of the amyloid core of Drosophila Orb2 isolated from head

Released:
DOI: 10.2210/pdb6vps/pdb
PDB entry 6vps coloured by chain, front view.
PDB entry 6vps coloured by chain, side view.
PDB entry 6vps coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila
Hervas R, Rau MJ, Park Y, Zhang W, Murzin AG, Fitzpatrick JAJ, Scheres SHW, Si K
Science 367 1230-1234 (2020)
Related structures: EMD-21316

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo nonamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194302 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Translational regulator orb2 Chains: A, B, C, D, E, F, G, H, I
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I
Length: 31 amino acids
Theoretical weight: 3.97 KDa
Source organism: Drosophila melanogaster
UniProt:
  • Canonical: Q9VSR3 (Residues: 176-206; Coverage: 4%)
Gene names: CG43782, orb2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.6Å
Relevant EMDB volumes: EMD-21316

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