Function and Biology Details
Reaction catalysed:
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- V-ATPase proteolipid subunit
- F/V-ATP synthase subunit C superfamily
- V-ATPase proteolipid subunit C-like domain
- V-ATPase proteolipid subunit C, eukaryotic
- Vacuolar (H+)-ATPase G subunit
- V-type ATPase subunit E
- V-type ATP synthase regulatory subunit B/beta
- P-loop containing nucleoside triphosphate hydrolase
31 more domains
Structure analysis Details
Assembly composition:
hetero 34-mer (preferred)
PDBe Complex ID:
PDB-CPX-109161 (preferred)
Entry contents:
16 distinct polypeptide molecules
Macromolecules (16 distinct):
V-type proton ATPase catalytic subunit A
Molecule details ›
Chains: A, B, C
Length: 617 amino acids
Theoretical weight: 68.34 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 617 amino acids
Theoretical weight: 68.34 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical:
D4A133 (Residues: 31-647; Coverage: 95%)
Sequence domains:
V-type proton ATPase subunit B, brain isoform
Molecule details ›
Chains: D, E, F
Length: 511 amino acids
Theoretical weight: 56.61 KDa
Source organism: Rattus norvegicus
UniProt:
Sequence domains:
Length: 511 amino acids
Theoretical weight: 56.61 KDa
Source organism: Rattus norvegicus
UniProt:
- Canonical: P62815 (Residues: 1-511; Coverage: 100%)
Sequence domains:
V-type proton ATPase subunit C 1
V-type proton ATPase subunit D
V-type proton ATPase subunit E 1
V-type proton ATPase subunit F
V-type proton ATPase subunit G
Type IV secretion protein Dot
V-type proton ATPase 116 kDa subunit a 1
V-ATPase proteolipid subunit C-like domain-containing protein
V-type proton ATPase subunit S1
V-type proton ATPase subunit
V-type proton ATPase subunit e 2
Ribonuclease K
V-type proton ATPase 16 kDa proteolipid subunit c
Renin receptor
