› 6vv5

Electron Microscopy
3.5Å resolution

Cryo-EM structure of porcine epidemic diarrhea virus (PEDV) spike protein

Released:
DOI: 10.2210/pdb6vv5/pdb
PDB entry 6vv5 coloured by chain, front view.
PDB entry 6vv5 coloured by chain, side view.
PDB entry 6vv5 coloured by chain, top view.
Source organism: Porcine epidemic diarrhea virus
Primary publication:
Structure and immune recognition of the porcine epidemic diarrhea virus spike protein.
Kirchdoerfer RN, Bhandari M, Martini O, Sewall LM, Bangaru S, Yoon KJ, Ward AB
OpenAccess logo Structure 29 385-392.e5 (2021)
PMID: 33378641
Related structures: EMD-21391

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197442 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Spike glycoprotein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 1356 amino acids
Theoretical weight: 148.46 KDa
Source organism: Porcine epidemic diarrhea virus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: S5RJN4 (Residues: 19-1322; Coverage: 94%)
Gene name: S
Sequence domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
2 bound ligands:
Ligand NAG 15 x NAG
Ligand PAM 6 x PAM
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.5Å
Relevant EMDB volumes: EMD-21391
Expression system: Spodoptera frugiperda

Quick links

Citations

3 review citations

Coronavirus accessory protein ORF3 biology and its contribution to viral behavior and pathogenesis.
Si et al. (2023)
2 more

14 mentions without citation

Antigen epitopes of animal coronaviruses: a mini-review.
Su et al. (2023)
13 more