Function and Biology

ClpAP Engaged2 State bound to RepA-GFP

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

EC 3.4.21.92: Endopeptidase Clp

Reaction catalysed:
Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-Casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec; and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
Systematic name:
-
Alternative Name(s):
  • ATP-dependent Clp protease
  • Caseinolytic protease
  • Clp protease
  • ClpP
  • Endopeptidase Ti
  • Protease Ti

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned