Function and Biology

Anomalous iodine signal reveals the position of I-paroxetine complexed with the serotonin transporter at the central site

Source organisms:
Biochemical function: not assigned
Biological process: not assigned
Cellular component: membrane

GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00209
Domain description: Sodium:neurotransmitter symporter family
Occurring in:
  1. Sodium-dependent serotonin transporter
The deposited structure of PDB entry 6w2c contains 1 copy of Pfam domain PF00209 (Sodium:neurotransmitter symporter family) in Sodium-dependent serotonin transporter. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000175
Domain description: Sodium:neurotransmitter symporter
Occurring in:
  1. Sodium-dependent serotonin transporter
IPR003597
Domain description: Immunoglobulin C1-set
Occurring in:
  1. 8B6 heavy chain antibody fragment
  2. 8B6 light chain antibody fragment
IPR013106
Domain description: Immunoglobulin V-set domain
Occurring in:
  1. 8B6 heavy chain antibody fragment
  2. 8B6 light chain antibody fragment
IPR036179
Domain description: Immunoglobulin-like domain superfamily
Occurring in:
  1. 8B6 heavy chain antibody fragment
  2. 8B6 light chain antibody fragment
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. 8B6 heavy chain antibody fragment
  2. 8B6 light chain antibody fragment
IPR007110
Domain description: Immunoglobulin-like domain
Occurring in:
  1. 8B6 heavy chain antibody fragment
  2. 8B6 light chain antibody fragment
IPR003599
Domain description: Immunoglobulin domain subtype
Occurring in:
  1. 8B6 heavy chain antibody fragment
  2. 8B6 light chain antibody fragment
IPR003006
Domain description: Immunoglobulin/major histocompatibility complex, conserved site
Occurring in:
  1. 8B6 light chain antibody fragment
IPR037272
Domain description: Sodium:neurotransmitter symporter superfamily
Occurring in:
  1. Sodium-dependent serotonin transporter